Endocrine Abstracts

Objective: Few studies have determined the effects of more than 5-10 years of GH replacement in adults on body composition and metabolic parameters.Design/Patients: In this prospective, single-center, open-label study, the effects of 15 years of GH replacement on body composition and metabolic parameters were determined in 156 hypopituitary adults (93 men) with adult onset GH deficiency (GHD). Mean age was 50.5 (range 22–74) years at study start. Bo...